nifedipine will boost the level or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Use Warning/Watch. Ethinyl estradiol may inhibit the clearance of benzodiazepines that undertake oxidation, therefore increasing serum concentrations of concomitantly administered benzodiazepines.
Since Valium provides a central anxious program depressant effect, patients ought to be encouraged in opposition to the simultaneous ingestion of Liquor and also other CNS-depressant drugs during Valium therapy.
Diazepam can be a medicine largely used to treat those with nervousness or a stress problem. Diazepam is used to deal with panic that's far more severe than that a result of the traditional strain of daily life.
Use or redistribution of any DrugBank content material or info needs a license and appropriate citations. Discuss with profits for commercial licensing. Make an application for a tutorial license.
benzhydrocodone/acetaminophen and diazepam the two raise sedation. Stay clear of read more or Use Alternate Drug. Restrict use to people for whom choice cure solutions are insufficient
The above focus on is a set of all attainable GABA(A) subunits which could participate in the formation from the pentameric receptor and isn't intended to indicate immediate a drug-protein interaction for every specific subunit.
Prescribers are strongly suggested to just take all affordable measures to ensure that caregivers entirely realize their job and obligations vis a vis the administration of diazepam rectal gel to people today inside their care
Keep track of for indications of urinary retention or decreased gastric motility if oliceridine is coadministered with anticholinergics.
Resulting from extended-performing metabolite, not thought of a drug of option during the aged; affiliated with falls
Stay away from or substitute A further drug for these drugs when possible. Assess for loss of therapeutic result if medication must be coadministered.
prednisone will lessen the extent or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
fluvoxamine will raise the stage or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Special care needs to be taken when diazepam is made use of during labor and supply, as high single doses might develop irregularities inside the fetal heart fee and hypotonia, poor sucking, hypothermia, and reasonable respiratory despair inside the neonates 15.